Oportunidades de Investigación Públicas

19-12-2023 Prototipo de microscopio volumétrico para neurofisiología óptica
Estamos desarrollando una nueva clase de microscopio volumétrico para realizar neurofisiología óptica rápida y localizada de todo el cerebro del pez cebra in vivo. A diferencia de los métodos de imágenes tridimensionales existentes que sacrifican sensibilidad, resolución celular o tasa de muestreo, nuestro enfoque original para el registro volumétrico es la formación de imágenes virtuales multifocales en una sola cámara usando componentes comerciales. En este proyecto implementaremos un prototipo de dispositivo de imagen que utiliza una cavidad óptica y lentes para enfocar un arreglo de imágenes virtuales en una cámara. Las tareas del proyecto incluirán construir un sistema optomecánico, alinear los componentes y realizar pruebas experimentales. Se valora la experiencia en proyectos de hardware, diseño óptico y electrónica, aunque no es necesaria.
Prerequisitos:  no tiene.

Tiene un método de evaluación Nota 1-7, con 10 créditos y tiene 2/4 vacantes disponibles

Mentor(es): Ver en la plataforma

Public Research Opportunities

19-12-2023 Volumetric Microscope Prototype for Optical Neurophysiology
We are developing a new class of volumetric microscope for fast, localized optical neurophysiology of the entire zebrafish brain in vivo. Unlike existing 3D imaging methods that sacrifice sensitivity, cellular resolution, or frame rate, our novel approach to volumetric recording utilizes multi-focal virtual image formation in a single camera using readily available commercial components. This project will focus on implementing a prototype imaging device that employs an optical cavity and lenses to project an array of virtual images onto a camera. Tasks will include building the optomechanical system, performing component alignment, and conducting experimental testing. Experience in hardware projects, optical design, and electronics is welcome but not essential.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 2/4 available vacants

Mentor(s): Open in the plataform
27-07-2023
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/1 available vacants

Mentor(s): Open in the plataform
11-07-2023 Microscope setup for wide-field optical neurophysiology
We are designing an optical neurophysiology microscope to enable measurement and stimulation of neural activity in thousands of neurons in a wide field of view spanning multiple regions of the murine brain. In this project we will plan and build the necessary hardware to integrate essential components of a custom microscope, including a camera, fluorescence filters, an array of micromirrors, light sources, among others. Tasks in this project will include designing mechanical installations, integrating mechanical, electronic and optical systems, and component alignment. Experience in mechanical design, 3D printing, optical design, hardware and electronics projects is welcome but not required
Keywords:       electrónica Hardware diseño óptico
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/2 available vacants

Mentor(s): Open in the plataform
11-07-2023 Construction of volumetric microscope prototype
We are developing a new class of volumetric microscope to enable fast, localized optical neurophysiology of the whole live zebrafish brain. Unlike existing three-dimensional imaging that compromises sensitivity, cell resolution, or framerate, our original approach to volumetric recording is multi-focal virtual image formation in a single camera using commercial components. In this project we will implement a prototype imaging device that uses an optical cavity to generate virtual arrays of images in a camera. Tasks in the project will include to build an optomechanical system, perform basic alignment, and experimental testing. Experience in hardware projects, optical design, and electronics is welcome but not required.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/2 available vacants

Mentor(s): Open in the plataform
07-07-2022 Microscope design for wide-field optical neurophysiology
We are designing an optical neurophysiology microscope to enable measurement and stimulation of neural activity in thousands of neurons in a wide field of view spanning multiple regions of the murine brain. In this project we will plan and build the necessary hardware to integrate essential components of a custom microscope, including a camera, fluorescence filters, an array of micromirrors, light sources, among others. Tasks in this project will include designing mechanical installations, integrating mechanical, electronic and optical systems, and component alignment. Experience in mechanical design, 3D printing, optical design, hardware and electronics projects is welcome but not required
Keywords:       electrónica Hardware diseño óptico
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/2 available vacants

Mentor(s): Open in the plataform
06-07-2022 All-optical electrophysiology signal extraction using deep learning
All-optical electrophysiology is revolutionizing neurobiology by enabling stimulation and measurement of large-scale neuronal activity non-invasively in the living brain of model animals. In our Laboratory we develop computational imaging techniques and apply them to optical electrophysiology measurements with high-speed optical section. In this project we will develop artificial intelligence methods to optimally identify neural signals from imperfect, mixed, and moving measurements. We seek to implement an algorithm that replicates the function of the human brain to identify these signals, which exceeds existing numerical algorithms. Expertise in programming, deep learning, and neurophysiology is welcome but not necessary.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/2 available vacants

Mentor(s): Open in the plataform
06-07-2022 Construction of volumetric microscope prototype
We are developing a new class of volumetric microscope to enable fast, localized optical neurophysiology of the whole live zebrafish brain. Unlike existing three-dimensional imaging that compromises sensitivity, cell resolution, or framerate, our original approach to volumetric recording is multi-focal virtual image formation in a single camera using commercial components. In this project we will implement a prototype imaging device that uses an optical cavity to generate virtual arrays of images in a camera. Tasks in the project will include to build an optomechanical system, perform basic alignment, and experimental testing. Experience in hardware projects, optical design, and electronics is welcome but not required.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/1 available vacants

Mentor(s): Open in the plataform
06-07-2022 Automatic 3D image integration in a portable device using deep learning
To prevent melanoma in patients with many lesions under surveillance, one challenge is the integration of dermatological images for effective lesion monitoring. We are developing a portable device based on NVidia microcomputer with stereo cameras to achieve the automatic integration of 3D images of the skin of patients. In this project we will implement machine learning techniques to merge and record images on dedicated embedded hardware. Tasks in this project will include operating hardware including microcomputers and cameras, developing and implementing computer vision and image processing algorithms. Experience in programming, computer vision, and machine learning is welcome but not necessary.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/3 available vacants

Mentor(s): Open in the plataform
19-07-2021 Development of an open hardware based wide field computational microscope for pollen recognition
Development of a working low-cost computational wide-field microscope for honey-pollen imaging (remotely at home) and analysis of generated data with MatLab or Python. A 3D printed prototype already exsists based on the publication 'Low-cost, sub-micron resolution, wide-field computational microscopy using opensource hardware’. Students should already have basic experience with prototyping and coding.
Prerequisites:  None.

Evaluation method: Nota 1-7, with 0/1 available vacants

Mentor(s): Open in the plataform